email: brattsten@aesop.rutgers.edu
Abstract: When insects are exposed to toxic chemicals and don't die, it is often because they have a biochemical resistance mechanism. They may be able to detoxify the compound very fast, or they may have an insensitive or protected target site. They may also have physiological, behavioral, or phenological resistance mechanisms. My research deals with the detoxification mechanisms in insects, such as cytochrome P450 and other defensive enzymes, and physiological adaptations to chemical stress.
Research Projects
- Biochemistry and molecular genetics of insect cytochrome P450
- Effects of herbicides and fungicides on insecticide toxicity
- Toxicology and control of mosquitoes
Recent Publications
- C. Suwanchaichinda, L. B. Brattsten 2002. Induction of microsomal cytochrome P450s by tire-leachate compounds, habitat components of Aedes albopictus mosquito larvae. Arch. Insect Biochem. Physiol., 49:71-79.
- F. M. deLame, J. J. Hong, P. W. Shearer, L. B. Brattsten 2001. Sex related differences in the resistance of Oriental fruit moth, Grapholita molesta (Busck), to organophosphorus insecticides. Pest Mgmt Sci., 57:6-12
- C. Suwanchaichinda, L. B. Brattsten 2001. Effects of exposure to pesticides on carbaryl toxicity and cytochrome P450 activities in Aedes albopictus larvae (Diptera:Culicidae). Pestic. Physiol. Biochem.,70:63-73
- L. R. M. Kao, C. F. Wilkinson, L. B. Brattsten 1995. In vivo effect of 2,4-D and atrazine on cytochrome P450 and insecticide toxicity in southern armyworm (Spodoptera eridania) larvae. Pestic. Sci., 45:331-334.
Teaching Portfolio
- Insect Biology 11 370 381, Team-taught with M. L. May and J. H. Lashomb. Lectures, labs, field trips, 4 credits, each fall.
- Insect Structure and Function 11 370 403 and 16 370 515, Team-taught with M. L. May, lectures, labs, 4 credits, every other fall semester.
- Toxicology of Pesticides 11 370 422 and 16 370 522, lectures, 3 credits, every other spring semester.
- Wine Insights 11 015 273, lectures, exercises, 1 credit, every semester.
Key Words
Biochemical toxicology, insect-plant interactions, insecticide resistance, biochemistry and molecular genetics of cytochrome P450, Spodoptera eridania, Aedes albopictus.